Third consensus on medical treatment of metastatic breast cancer

被引：144

作者：

Beslija, S. ^{[2
]}

Bonneterre, J. ^{[3
]}

Burstein, H. J. ^{[4
]}

Cocquyt, V. ^{[5
]}

Gnant, M. ^{[6
]}

Heinemann, V. ^{[7
]}

Jassem, J. ^{[8
]}

Koestler, W. J. ^{[1
]}

Krainer, M. ^{[1
]}

Menard, S. ^{[9
]}

Petit, T. ^{[10
]}

Petruzelka, L. ^{[11
]}

Possinger, K. ^{[12
]}

Schmid, P. ^{[13
]}

Stadtmauer, E. ^{[14
]}

Stockler, M. ^{[15
,16
]}

Van Belle, S. ^{[5
]}

Vogel, C. ^{[17
]}

Wilcken, N. ^{[18
]}

Wiltschke, C. ^{[1
]}

Zielinski, C. C. ^{[1
,19
]}

Zwierzina, H. ^{[20
]}

机构：

[1] Med Univ Vienna, Dept Med 1, Div Clin Oncol, A-1090 Vienna, Austria

[2] Inst Oncol, Sarajevo, Bosnia & Herceg

[3] Ctr Oscar Lambret, F-59020 Lille, France

[4] Dana Farber Canc Inst, Boston, MA 02115 USA

[5] Univ Ziekenhuis St Rafael, Oncolog Centrum, Ghent, Belgium

[6] Med Univ Vienna, Dept Surg, Vienna, Austria

[7] Univ Munich, Klinikum Grosshadern, Med Klin & Poliklin 3, D-8000 Munich, Germany

[8] Med Univ, Dept Radiotherapy & Oncol, Gdansk, Poland

[9] Ist Tumori, Milan, Italy

[10] Ctr Paul Strauss, Strasbourg, France

[11] Charles Univ Prague, Dept Oncol, Prague, Czech Republic

[12] Med Klin Charite, Berlin, Germany

[13] Univ London Imperial Coll Sci Technol & Med, Charing Cross Hosp, London, England

[14] Univ Penn, Ctr Canc, Philadelphia, PA 19104 USA

[15] Univ Sydney, Concord Hosp, Sydney, NSW 2006, Australia

[16] Royal Prince Alfred Hosp, Sydney Canc Ctr, Sydney, NSW, Australia

[17] Breast Canc Aptium Oncol Lynn Canc Inst W, Boca Raton, FL USA

[18] Westmead Hosp, Dept Med Oncol & Palliat Care, Sydney, NSW, Australia

[19] Cent European Cooperat Oncol Grp, Vienna, Austria

[20] Med Univ Innsbruck, Dept Med 1, Innsbruck, Austria

来源：

ANNALS OF ONCOLOGY | 2009年 / 20卷 / 11期

关键词：

diagnosis; metastatic breast cancer; prognosis; treatment; PHASE-II TRIAL; PEGYLATED LIPOSOMAL DOXORUBICIN; HEAVILY PRETREATED PATIENTS; EVERY-2-WEEK DARBEPOETIN-ALPHA; CHEMOTHERAPY-INDUCED ANEMIA; COLONY-STIMULATING FACTOR; IN-SITU HYBRIDIZATION; WEEKLY EPOETIN-ALPHA; 1ST-LINE TREATMENT; SKELETAL COMPLICATIONS;

D O I：

10.1093/annonc/mdp261

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Design: To provide timely and evidence-based recommendations for the diagnostic workup and treatment of patients with MBC, an international expert panel reviewed and discussed the evidence available from clinical trials regarding diagnostic, therapeutic and supportive measures with emphasis on their impact on the quality of life and overall survival of patients with MBC. Results: Evidence-based recommendations for the diagnostic workup, endocrine therapy, chemotherapy, use of targeted therapies and bisphosphonates, surgical treatment and supportive care measures in the management of patients with MBC were formulated. Conclusions: The present consensus manuscript updates evidence-based recommendations for state-of-the-art treatment of MBC depending on disease-associated and biological variables.

引用

页码：1771 / 1785

页数：15

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