Malnutrition and childhood epilepsy in developing countries

被引:26
作者
Hackett, R
Iype, T
机构
[1] Manchester Royal Infirm, Epilepsy Clin, Manchester M13 9WL, Lancs, England
[2] Trichur Med Coll, Dept Neurol, Trichur, Kerala, India
来源
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 2001年 / 10卷 / 08期
关键词
malnutrition; epilepsy; children; developing country;
D O I
10.1053/seiz.2001.0532
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A high prevalence of epilepsy in children is frequently found in developing countries. Though high rates of acquired brain injury may contribute, the possibility that malnutrition may lower seizure threshold has rarely been examined. This review suggests potential biochemical mechanisms that could adversely affect seizure threshold, particularly the effect of malnutrition on inhibitory neurotransmitters and electrolytes. Supporting evidence from animal research and epidemiological findings in children are discussed. (C) 2001 BEA Trading Ltd.
引用
收藏
页码:554 / 558
页数:5
相关论文
共 54 条
[1]   ERYTHROCYTIC ENZYMES AND AMINO-ACIDS RELATED TO GLUTAMIC-ACID METABOLISM IN CHILDHOOD HYPOPROTEINEMIC STATES [J].
AGARWAL, KN ;
BHATIA, BD ;
BATTA, RK ;
SINGLA, PN ;
SHANKAR, R .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1981, 34 (05) :924-927
[2]   Protein malnutrition alters the cholinergic and GABAergic systems of the hippocampal formation of the adult rat: An immunocytochemical study [J].
Andrade, JP ;
PaulaBarbosa, MM .
NEUROSCIENCE LETTERS, 1996, 211 (03) :211-215
[3]  
[Anonymous], 1967, LANCET, V1, P712
[4]  
ANTENER I, 1978, HELV PAEDIATR ACTA, V33, P543
[5]  
Asindi A A, 1995, Afr J Med Med Sci, V24, P243
[6]   EPILEPSY IN PAKISTAN - A POPULATION-BASED EPIDEMIOLOGIC-STUDY [J].
AZIZ, H ;
ALI, SM ;
FRANCES, P ;
KHAN, MI ;
HASAN, KZ .
EPILEPSIA, 1994, 35 (05) :950-958
[7]   NEUROLOGICAL MANIFESTATIONS OF MAGNESIUM DEFICIENCY IN INFANTILE GASTRO-ENTERITIS AND MALNUTRITION [J].
BACK, EH ;
MONTGOMERY, RD ;
WARD, EE .
ARCHIVES OF DISEASE IN CHILDHOOD, 1962, 37 (191) :106-&
[8]   VIRAL ENCEPHALITIS [J].
BALE, JF .
MEDICAL CLINICS OF NORTH AMERICA, 1993, 77 (01) :25-42
[9]   HYPOGLYCEMIA DURING DIARRHEA IN CHILDHOOD - PREVALENCE, PATHOPHYSIOLOGY, AND OUTCOME [J].
BENNISH, ML ;
AZAD, AK ;
RAHMAN, O ;
PHILLIPS, RE .
NEW ENGLAND JOURNAL OF MEDICINE, 1990, 322 (19) :1357-1363
[10]   Magnitude of the disease burden from neurocysticercosis in a developing country [J].
Bern, C ;
Garcia, HH ;
Evans, C ;
Gonzalez, AE ;
Verastegui, M ;
Tsang, VCW ;
Gilman, RH .
CLINICAL INFECTIOUS DISEASES, 1999, 29 (05) :1203-1209