Daptomycin-rifampin for a recurrent MRSA joint infection unresponsive to vancomycin-based therapy

被引:32
作者
Burns, CA [1 ]
机构
[1] Ocala Reg Med Ctr, Ocala, FL 34478 USA
关键词
D O I
10.1080/00365540500277292
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A 54-y-old morbidly obese male presented with methicillin-resistant Staphylococcus aureus ( MRSA) bacteremia secondary to chronic right hip arthroplasty infection. Bacteremia persisted despite prolonged vancomycin-based therapy ( MIC <= 1 mu g/ml) and prosthetic removal. Adding daptomycin-rifampin resolved bacteremia within 48 h; hip cultures remained negative post-discharge. This case describes alternative treatment for chronic MRSA infections.
引用
收藏
页码:133 / 136
页数:4
相关论文
共 18 条
[1]   Trends in the treatment of orthopaedic prosthetic infections [J].
Bernard, L ;
Hoffmeyer, P ;
Assal, M ;
Vaudaux, P ;
Schrenzel, J ;
Lew, D .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2004, 53 (02) :127-129
[2]  
*CDC, NATL NOS INF SURV SY
[3]   Bactericidal activities of daptomycin, quinupristin-dalfopristin, and linezolid against vancomycin-resistant Staphylococcus aureus in an in vitro pharmacodynamic model with simulated endocardial vegetations [J].
Cha, R ;
Brown, WJ ;
Rybak, MJ .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (12) :3960-3963
[4]   Antibiotic treatment of Gram-positive bone and joint infections [J].
Darley, ESR ;
MacGowan, AP .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2004, 53 (06) :928-935
[5]   Severe myopathy and possible hepatotoxicity related to daptomycin [J].
Echevarria, K ;
Datta, P ;
Cadena, J ;
Lewis, JS .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 55 (04) :599-600
[6]   In vitro activity of daptomycin against gram-positive European clinical isolates with defined resistance determinants [J].
Fluit, AC ;
Schmitz, FJ ;
Verhoef, J ;
Milatovic, D .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (03) :1007-1011
[7]   Risk of methicillin-resistant Staphylococcus aureus infection after previous infection or colonization [J].
Huang, SS ;
Platt, R .
CLINICAL INFECTIOUS DISEASES, 2003, 36 (03) :281-285
[8]   Prosthetic joint infections: Bane of orthopedists, challenge for infectious disease specialists [J].
Lentino, JR .
CLINICAL INFECTIOUS DISEASES, 2003, 36 (09) :1157-1161
[9]   SLOW RESPONSE TO VANCOMYCIN OR VANCOMYCIN PLUS RIFAMPIN IN METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS ENDOCARDITIS [J].
LEVINE, DP ;
FROMM, BS ;
REDDY, BR .
ANNALS OF INTERNAL MEDICINE, 1991, 115 (09) :674-680
[10]   COMPARATIVE-EVALUATION OF DAPTOMYCIN (LY146032) AND VANCOMYCIN IN THE TREATMENT OF EXPERIMENTAL METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS OSTEOMYELITIS IN RABBITS [J].
MADER, JT ;
ADAMS, K .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1989, 33 (05) :689-692