Reinvestigation of the dimerisation process forming isoglaucanic acid

被引：28

作者：

Baldwin, JE ^{[1
]}

Beyeler, A ^{[1
]}

Cox, RJ ^{[1
]}

Keats, C ^{[1
]}

Pritchard, GJ ^{[1
]}

Adlington, RM ^{[1
]}

Watkin, DJ ^{[1
]}

机构：

[1] Dyson Perrins Lab, Oxford OX1 3QY, England

来源：

TETRAHEDRON | 1999年 / 55卷 / 23期

关键词：

D O I：

10.1016/S0040-4020(99)00360-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The base catalysed dimerisation of 2-[(E)-1'-pentenyl]-3-methyl maleic anhydride has been extensively reinvestigated and the relative stereochemistry of an isoglaucanic acid derivative product has been determined by X-ray crystallography. The dimerisation process has been improved and the work up has been simplified, doubling the yield. Further co-products have been isolated and characterised from which a stepwise mechanism is proposed. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：7363 / 7374

页数：12

共 22 条

[1]

Armstrong A, 1998, SYNLETT, P552

[2] NONADRIDES .4. CONSTITUTION AND STEREOCHEMISTRY OF BYSSOCHLAMIC ACID [J].