Membrane repair:: Ca2+-ellicited lysosomal exocytosis

被引:60
作者
Gerasimenko, JV [1 ]
Gerasimenko, OV [1 ]
Petersen, OH [1 ]
机构
[1] Univ Liverpool, Physiol Lab, MRC, Secretory Control Res Grp, Liverpool L69 3BX, Merseyside, England
基金
英国医学研究理事会;
关键词
D O I
10.1016/S0960-9822(01)00577-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cells in exposed positions are subject to injury and therefore need membrane repair mechanisms. Ca2+ entry inevitably follows membrane rupture and recent studies indicate that this elicits repair via Ca2+-activated exocytosis of lysosomes, regulated by lysosomal synaptotagmin VII.
引用
收藏
页码:R971 / R974
页数:4
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