Deltamethrin resistance in the codling moth (Lepidoptera: Tortricidae):: inheritance and number of genes involved

The inheritance of deltamethrin resistance in Cydia pomonella (L.) has been investigated by crossing a resistant (Rv) and a susceptible (Sv) strain. derived from a population collected in south-eastern France in 1995. Deltamethrin resistance was suspected to be under the control of a kdr-type allele and an enhanced mixed-function oxidase (mfo). F-1 and F-2 progenies were therefore tested through dose-response and enzyme assays. Dose-response relationships indicated that resistance was inherited as an autosomal incompletely recessive (D = -0.199) character. involving at least two genes. Enzyme measures suggested the contribution of 1.2 genes to the expression of mfo, with incomplete dominance (D=0.460). Our results support the hypothesis of a polygenic response to deltamethrin selection in the Rv strain. including a major kdr-type allele with a minor effect of mfos. In the light of these findings. we consider the resistance in codling moth populations in south-eastern France as a product of an adaptive sequential selection process. occurring through the sequential addition of resistance genes.