Controversies at the cytoplasmic face of the cadherin-based adhesion complex

被引：140

作者：

Provost, E ^{[1
]}

Rimm, DL ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Dept Pathol, New Haven, CT 06510 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 05期

关键词：

D O I：

10.1016/S0955-0674(99)00015-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cadherin-mediated cell-cell interactions are modulated by protein interactions at the cytoplasmic face of the membrane. Recent work has shown that phosphorylation of both p120(ctn) and beta-catenin affects their interaction with cadherins and the molecular connections to the cytoskeleton. The cytoskeletal connections most probably include interactions between alpha-catenin, and/or alpha-actinin, vinculin, ZO-1, actin and possibly spectrin.

引用

页码：567 / 572

页数：6

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