Gut microbiome and intestinal barrier failure - The "Achilles heel" in hepatology?

被引:32
作者
Benten, Daniel [1 ]
Wiest, Reiner [2 ]
机构
[1] Univ Hosp Hamburg Eppendorf, Dept Gastroenterol & Hepatol, Hamburg, Germany
[2] Inselspital Bern, Dept Visceral Surg & Med, Bern, Switzerland
关键词
BACTERIAL TRANSLOCATION; LIVER; OVERGROWTH; ENDOTOXEMIA; CROSSTALK;
D O I
10.1016/j.jhep.2012.03.003
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
引用
收藏
页码:1221 / 1223
页数:3
相关论文
共 19 条
[1]
Bauer TM, 2002, AM J GASTROENTEROL, V97, P2364
[2]
TRANSLOCATION OF CERTAIN INDIGENOUS BACTERIA FROM THE GASTRO-INTESTINAL TRACT TO THE MESENTERIC LYMPH-NODES AND OTHER ORGANS IN A GNOTOBIOTIC MOUSE MODEL [J].
BERG, RD ;
GARLINGTON, AW .
INFECTION AND IMMUNITY, 1979, 23 (02) :403-411
[3]
Characterization of Fecal Microbial Communities in Patients with Liver Cirrhosis [J].
Chen, Yanfei ;
Yang, Fengling ;
Lu, Haifeng ;
Wang, Baohong ;
Chen, Yunbo ;
Lei, Dajiang ;
Wang, Yuezhu ;
Zhu, Baoli ;
Li, Lanjuan .
HEPATOLOGY, 2011, 54 (02) :562-572
[4]
Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease [J].
Fouts, Derrick E. ;
Torralba, Manolito ;
Nelson, Karen E. ;
Brenner, David A. ;
Schnabl, Bernd .
JOURNAL OF HEPATOLOGY, 2012, 56 (06) :1283-1292
[5]
Gäbele E, 2011, J HEPATOL, V55, P1391, DOI 10.1016/j.jhep.2011.02.035
[6]
Secretory IgA mediates bacterial translocation to dendritic cells in mouse Peyer's patches with restriction to mucosal compartment [J].
Kadaoui, Khalil A. ;
Corthesy, Blaise .
JOURNAL OF IMMUNOLOGY, 2007, 179 (11) :7751-7757
[7]
Rifaximin reduces endotoxemia and improves liver function and disease severity in patients with decompensated cirrhosis [J].
Kalambokis, Georgios N. ;
Tsianos, Epameinondas V. .
HEPATOLOGY, 2012, 55 (02) :655-656
[8]
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity [J].
Kawai, Taro ;
Akira, Shizuo .
IMMUNITY, 2011, 34 (05) :637-650
[9]
Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats [J].
Lorenzo-Zúñiga, V ;
Bartolí, R ;
Planas, R ;
Hofmann, AF ;
Viñado, B ;
Hagey, LR ;
Hernández, JM ;
Mañé, J ;
Alvarez, MA ;
Ausina, V ;
Gassull, MA .
HEPATOLOGY, 2003, 37 (03) :551-557
[10]
Epithelial Barriers in Homeostasis and Disease [J].
Marchiando, Amanda M. ;
Graham, W. Vallen ;
Turner, Jerrold R. .
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE, 2010, 5 :119-144