Bacterial contributions to mammalian gut development

被引:422
作者
Hooper, LV [1 ]
机构
[1] Univ Texas, SW Med Ctr, Ctr Immunol, Dallas, TX 75390 USA
关键词
D O I
10.1016/j.tim.2004.01.001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The mammalian gut has coevolved over millions of years with a vast consortium of microbes. From birth, this population is in continuous and intimate contact with intestinal tissues. Recent results indicate that indigenous bacteria play a crucial inductive role in gut development during early postnatal life. These findings have revealed that the mammalian intestine is poised for interaction with its prokaryotic partners, which are essential for its normal development.
引用
收藏
页码:129 / 134
页数:6
相关论文
共 42 条
  • [1] NUTRITIONAL AND DEVELOPMENTAL REGULATION OF GLYCOSYLATION PROCESSES IN DIGESTIVE ORGANS
    BIOL, MC
    MARTIN, A
    LOUISOT, P
    [J]. BIOCHIMIE, 1992, 74 (01) : 13 - 24
  • [2] A model of host-microbial interactions in an open mammalian ecosystem
    Bry, L
    Falk, PG
    Midtvedt, T
    Gordon, JI
    [J]. SCIENCE, 1996, 273 (5280) : 1380 - 1383
  • [3] Darveau RP, 2003, ASM NEWS, V69, P186
  • [4] An important regulatory role for CD4+CD8αα T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease
    Das, G
    Augustine, MM
    Das, J
    Bottomly, K
    Ray, P
    Ray, A
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (09) : 5324 - 5329
  • [5] De Winter H, 1999, AM J PHYSIOL-GASTR L, V276, pG1317, DOI 10.1152/ajpgi.1999.276.6.G1317
  • [6] Evolutionary developmental biology - It's the ecology, stupid!
    Dusheck, J
    [J]. NATURE, 2002, 418 (6898) : 578 - 579
  • [7] Vibrio fischeri lipopolysaccharide induces developmental apoptosis, but not complete morphogenesis, of the Euprymna scolopes symbiotic light organ
    Foster, JS
    Apicella, MA
    McFall-Ngai, MJ
    [J]. DEVELOPMENTAL BIOLOGY, 2000, 226 (02) : 242 - 254
  • [8] Induction of apoptosis by cooperative bacteria in the morphogenesis of host epithelial tissues
    Foster, JS
    McFall-Ngai, MJ
    [J]. DEVELOPMENT GENES AND EVOLUTION, 1998, 208 (06) : 295 - 303
  • [9] Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice
    Garabedian, EM
    Roberts, LJJ
    McNevin, MS
    Gordon, JI
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (38) : 23729 - 23740
  • [10] INFLAMMATORY BOWEL-DISEASE AND DOMESTIC HYGIENE IN INFANCY
    GENT, AE
    HELLIER, MD
    GRACE, RH
    SWARBRICK, ET
    COGGON, D
    [J]. LANCET, 1994, 343 (8900) : 766 - 767