Current status of low density lipoprotein-apheresis for the therapy of severe hyperlipidemia

被引：23

作者：

Gordon, BR ^{[1
]}

Saal, SD ^{[1
]}

机构：

[1] NEW YORK HOSP,ROGOSIN HOSP,CORNELL MED CTR,NEW YORK,NY 10021

来源：

CURRENT OPINION IN LIPIDOLOGY | 1996年 / 7卷 / 06期

关键词：

D O I：

10.1097/00041433-199612000-00007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The use of LDL-apheresis to treat patients with severe hypercholesterolemia has gained wider clinical acceptance during the past 2-3 years, particularly in patients with coronary artery disease, Systems utilizing immunoadsorption columns, dextran sulfate cellulose columns and heparin precipitation have been most commonly employed. New or improved technologies include whole-blood compatible columns, double-filtration plasmapheresis and lipoprotein (a)-apheresis. The mechanisms for clinical improvement extend beyond simple regression of atherosclerotic plaque.

引用

页码：381 / 384

页数：4

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