Receptor signaling: When dimerization is not enough

被引：150

作者：

Jiang, GQ ^{[1
]}

Hunter, T ^{[1
]}

机构：

[1] Salk Inst Biol Studies, Mol Biol & Virol Lab, La Jolla, CA 92037 USA

来源：

CURRENT BIOLOGY | 1999年 / 9卷 / 15期

关键词：

D O I：

10.1016/S0960-9822(99)80357-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Activation of receptors that signal via tyrosine kinase domains has been thought to involve receptor dimerization and transphosphorylation of juxtaposed catalytic domains. Recent results suggest things might be more complex - specific intersubunit conformational changes within a dimer can also be important.

引用

页码：R568 / R571

页数：4

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