Mammalian artificial chromosomes

被引：19

作者：

Brown, W ^{[1
]}

Heller, R ^{[1
]}

Loupart, ML ^{[1
]}

Shen, MH ^{[1
]}

Chand, A ^{[1
]}

机构：

[1] UNIV EDINBURGH,CTR GENOME RES,EDINBURGH EH9 3JQ,MIDLOTHIAN,SCOTLAND

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1996年 / 6卷 / 03期

关键词：

D O I：

10.1016/S0959-437X(96)80003-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The development of candidate vectors and of techniques for their manipulation by sequence targeting suggest that a mini-chromosome vector system for the mouse germline may be at hand. Mini-chromosome vectors should allow new sorts of genetic problems to be addressed experimentally and may accelerate the process of gene identification.

引用

页码：281 / 288

页数：8

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