A practical one-pot synthesis of enantiopure unsymmetrical salen ligands

被引:84
作者
Holbach, M
Zheng, XL
Burd, C
Jones, CW
Weck, M [1 ]
机构
[1] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA
[2] Georgia Inst Technol, Sch Chem & Biomol Engn, Atlanta, GA 30332 USA
关键词
D O I
10.1021/jo052614y
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A practical, one-pot synthesis of enantiopure unsymmetrical salen ligands is described, using a 1: 1: 1 molar ratio of a chiral diamine and two different salicylaldehydes. The new synthetic protocol can be readily performed in good yields (60-85%) on a multigram scale with good tolerance toward various functional groups.
引用
收藏
页码:2903 / 2906
页数:4
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