共 16 条
Quantitative variations in the vaginal bacterial population associated with asymptomatic infections: a real-time polymerase chain reaction study
被引:52
作者:

Biagi, E.
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机构:
Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy

Vitali, B.
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机构:
Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy

Pugliese, C.
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h-index: 0
机构:
Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy

Candela, M.
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机构:
Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy

Donders, G. G. G.
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h-index: 0
机构:
Femicare Clin Res Women, Tienen, Belgium
Catholic Univ Louvain, Dept Obstet & Gynaecol, Gen Hosp Heilig Hart Tienen, B-3000 Louvain, Belgium
Catholic Univ Louvain, Univ Hosp Gasthuisberg, B-3000 Louvain, Belgium Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy

Brigidi, P.
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机构:
Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy
机构:
[1] Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy
[2] Femicare Clin Res Women, Tienen, Belgium
[3] Catholic Univ Louvain, Dept Obstet & Gynaecol, Gen Hosp Heilig Hart Tienen, B-3000 Louvain, Belgium
[4] Catholic Univ Louvain, Univ Hosp Gasthuisberg, B-3000 Louvain, Belgium
关键词:
GROUP-SPECIFIC PRIMERS;
GARDNERELLA-VAGINALIS;
PREDOMINANT BACTERIA;
LACTOBACILLUS SPP;
MYCOPLASMA-HOMINIS;
HUMAN FECES;
VAGINOSIS;
PCR;
WOMEN;
CANDIDIASIS;
D O I:
10.1007/s10096-008-0617-0
中图分类号:
R51 [传染病];
学科分类号:
100401 ;
摘要:
The real-time polymerase chain reaction (PCR) quantification of several vaginal bacterial groups in healthy women and patients developing asymptomatic bacterial vaginosis (BV) and candidiasis (CA) was performed. Statistical analysis revealed that the BV condition is characterised by a great variability among subjects and that it is associated with a significant increase of Prevotella, Atopobium, Veillonella and Gardnerella vaginalis, and a drop in Lactobacillus. On the contrary, the vaginal microflora of healthy women and patients developing CA was found to be homogeneous and stable over time.
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页码:281 / 285
页数:5
相关论文
共 16 条
[1]
Quantitative determination by real-time PCR of four vaginal Lactobacillus species, Gardnerella vaginalis and Atopobium vaginae indicates an inverse relationship between L. gasseri and L. iners
[J].
De Backer, Ellen
;
Verhelst, Rita
;
Verstraelen, Hans
;
Alqumber, Mohammed A.
;
Burton, Jeremy P.
;
Tagg, John R.
;
Temmerman, Marleen
;
Vaneechoutte, Mario
.
BMC MICROBIOLOGY,
2007, 7 (1)

De Backer, Ellen
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Otago, Dept Microbiol & Immunol, Dunedin, New Zealand Univ Ghent, Ghent Univ Hosp, Dept Clin Chem Microbiol & Immunol, Ghent, Belgium

Verhelst, Rita
论文数: 0 引用数: 0
h-index: 0
机构: Univ Ghent, Ghent Univ Hosp, Dept Clin Chem Microbiol & Immunol, Ghent, Belgium

Verstraelen, Hans
论文数: 0 引用数: 0
h-index: 0
机构: Univ Ghent, Ghent Univ Hosp, Dept Clin Chem Microbiol & Immunol, Ghent, Belgium

Alqumber, Mohammed A.
论文数: 0 引用数: 0
h-index: 0
机构: Univ Ghent, Ghent Univ Hosp, Dept Clin Chem Microbiol & Immunol, Ghent, Belgium

Burton, Jeremy P.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Otago, BLIS Technol Ltd, Ctr Innovat, Dunedin, New Zealand Univ Ghent, Ghent Univ Hosp, Dept Clin Chem Microbiol & Immunol, Ghent, Belgium

Tagg, John R.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Otago, Dept Microbiol & Immunol, Dunedin, New Zealand Univ Ghent, Ghent Univ Hosp, Dept Clin Chem Microbiol & Immunol, Ghent, Belgium

Temmerman, Marleen
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Ghent, Ghent Univ Hosp, Dept Obstet & Gynaecol, Ghent, Belgium Univ Ghent, Ghent Univ Hosp, Dept Clin Chem Microbiol & Immunol, Ghent, Belgium

Vaneechoutte, Mario
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Ghent, Ghent Univ Hosp, Dept Clin Chem Microbiol & Immunol, Ghent, Belgium Univ Ghent, Ghent Univ Hosp, Dept Clin Chem Microbiol & Immunol, Ghent, Belgium
[2]
HISTORY AND REVIEW OF BACTERIAL VAGINOSIS
[J].
ESCHENBACH, DA
.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY,
1993, 169 (02)
:441-445

ESCHENBACH, DA
论文数: 0 引用数: 0
h-index: 0
机构: Department of Obstetrics and Gynecology, University of Washington, Seattle, WA
[3]
Molecular identification of bacteria associated with bacterial vaginosis
[J].
Fredricks, DN
;
Fiedler, TL
;
Marrazzo, JM
.
NEW ENGLAND JOURNAL OF MEDICINE,
2005, 353 (18)
:1899-1911

Fredricks, DN
论文数: 0 引用数: 0
h-index: 0
机构: Fred Hutchinson Canc Res Ctr, Program Infect Dis, Seattle, WA 98109 USA

Fiedler, TL
论文数: 0 引用数: 0
h-index: 0
机构: Fred Hutchinson Canc Res Ctr, Program Infect Dis, Seattle, WA 98109 USA

Marrazzo, JM
论文数: 0 引用数: 0
h-index: 0
机构: Fred Hutchinson Canc Res Ctr, Program Infect Dis, Seattle, WA 98109 USA
[4]
Asymptomatic bacterial vaginosis: is it time to treat?
[J].
Gibbs, Ronald S.
.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY,
2007, 196 (06)
:495-496

Gibbs, Ronald S.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Colorado, Sch Med, Dept Obstet & Gynecol, Denver, CO 80262 USA Univ Colorado, Sch Med, Dept Obstet & Gynecol, Denver, CO 80262 USA
[5]
Molecular diversity of Lactobacillus spp. and other lactic acid bacteria in the human intestine as determined by specific amplification of 16S ribosomal DNA
[J].
Heilig, HGHJ
;
Zoetendal, EG
;
Vaughan, EE
;
Marteau, P
;
Akkermans, ADL
;
de Vos, WM
.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY,
2002, 68 (01)
:114-123

Heilig, HGHJ
论文数: 0 引用数: 0
h-index: 0
机构: Univ Wageningen & Res Ctr, Microbiol Lab, NL-6703 CT Wageningen, Netherlands

Zoetendal, EG
论文数: 0 引用数: 0
h-index: 0
机构: Univ Wageningen & Res Ctr, Microbiol Lab, NL-6703 CT Wageningen, Netherlands

Vaughan, EE
论文数: 0 引用数: 0
h-index: 0
机构: Univ Wageningen & Res Ctr, Microbiol Lab, NL-6703 CT Wageningen, Netherlands

Marteau, P
论文数: 0 引用数: 0
h-index: 0
机构: Univ Wageningen & Res Ctr, Microbiol Lab, NL-6703 CT Wageningen, Netherlands

Akkermans, ADL
论文数: 0 引用数: 0
h-index: 0
机构: Univ Wageningen & Res Ctr, Microbiol Lab, NL-6703 CT Wageningen, Netherlands

de Vos, WM
论文数: 0 引用数: 0
h-index: 0
机构: Univ Wageningen & Res Ctr, Microbiol Lab, NL-6703 CT Wageningen, Netherlands
[6]
Microbes on the human vaginal epithelium
[J].
Hyman, RW
;
Fukushima, M
;
Diamond, L
;
Kumm, J
;
Giudice, LC
;
Davis, RW
.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,
2005, 102 (22)
:7952-7957

Hyman, RW
论文数: 0 引用数: 0
h-index: 0
机构: Stanford Univ, Genome Technol Ctr, Palo Alto, CA 94304 USA

Fukushima, M
论文数: 0 引用数: 0
h-index: 0
机构: Stanford Univ, Genome Technol Ctr, Palo Alto, CA 94304 USA

Diamond, L
论文数: 0 引用数: 0
h-index: 0
机构: Stanford Univ, Genome Technol Ctr, Palo Alto, CA 94304 USA

Kumm, J
论文数: 0 引用数: 0
h-index: 0
机构: Stanford Univ, Genome Technol Ctr, Palo Alto, CA 94304 USA

Giudice, LC
论文数: 0 引用数: 0
h-index: 0
机构: Stanford Univ, Genome Technol Ctr, Palo Alto, CA 94304 USA

Davis, RW
论文数: 0 引用数: 0
h-index: 0
机构: Stanford Univ, Genome Technol Ctr, Palo Alto, CA 94304 USA
[7]
Use of 16S rRNA gene-targeted group-specific primers for real-time PCR analysis of predominant bacteria in human feces
[J].
Matsuki, T
;
Watanabe, K
;
Fujimoto, J
;
Takada, T
;
Tanaka, R
.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY,
2004, 70 (12)
:7220-7228

Matsuki, T
论文数: 0 引用数: 0
h-index: 0
机构:
Yakult Cent Inst Microbiol Res, Tokyo 1868650, Japan Yakult Cent Inst Microbiol Res, Tokyo 1868650, Japan

Watanabe, K
论文数: 0 引用数: 0
h-index: 0
机构:
Yakult Cent Inst Microbiol Res, Tokyo 1868650, Japan Yakult Cent Inst Microbiol Res, Tokyo 1868650, Japan

Fujimoto, J
论文数: 0 引用数: 0
h-index: 0
机构:
Yakult Cent Inst Microbiol Res, Tokyo 1868650, Japan Yakult Cent Inst Microbiol Res, Tokyo 1868650, Japan

Takada, T
论文数: 0 引用数: 0
h-index: 0
机构:
Yakult Cent Inst Microbiol Res, Tokyo 1868650, Japan Yakult Cent Inst Microbiol Res, Tokyo 1868650, Japan

Tanaka, R
论文数: 0 引用数: 0
h-index: 0
机构:
Yakult Cent Inst Microbiol Res, Tokyo 1868650, Japan Yakult Cent Inst Microbiol Res, Tokyo 1868650, Japan
[8]
Development of 16S rRNA-gene-targeted group-specific primers for the detection and identification of predominant bacteria in human feces
[J].
Matsuki, T
;
Watanabe, K
;
Fujimoto, J
;
Miyamoto, Y
;
Takada, T
;
Matsumoto, K
;
Oyaizu, H
;
Tanaka, R
.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY,
2002, 68 (11)
:5445-5451

Matsuki, T
论文数: 0 引用数: 0
h-index: 0
机构: Yakult Cent Inst Microbiol Res, Kunitachi, Tokyo 1868650, Japan

Watanabe, K
论文数: 0 引用数: 0
h-index: 0
机构: Yakult Cent Inst Microbiol Res, Kunitachi, Tokyo 1868650, Japan

Fujimoto, J
论文数: 0 引用数: 0
h-index: 0
机构: Yakult Cent Inst Microbiol Res, Kunitachi, Tokyo 1868650, Japan

Miyamoto, Y
论文数: 0 引用数: 0
h-index: 0
机构: Yakult Cent Inst Microbiol Res, Kunitachi, Tokyo 1868650, Japan

Takada, T
论文数: 0 引用数: 0
h-index: 0
机构: Yakult Cent Inst Microbiol Res, Kunitachi, Tokyo 1868650, Japan

Matsumoto, K
论文数: 0 引用数: 0
h-index: 0
机构: Yakult Cent Inst Microbiol Res, Kunitachi, Tokyo 1868650, Japan

Oyaizu, H
论文数: 0 引用数: 0
h-index: 0
机构: Yakult Cent Inst Microbiol Res, Kunitachi, Tokyo 1868650, Japan

Tanaka, R
论文数: 0 引用数: 0
h-index: 0
机构: Yakult Cent Inst Microbiol Res, Kunitachi, Tokyo 1868650, Japan
[9]
Development of an extensive set of 16S rDNA-targeted primers for quantification of pathogenic and indigenous bacteria in faecal samples by real-time PCR
[J].
Rinttilä, T
;
Kassinen, A
;
Malinen, E
;
Krogius, L
;
Palva, A
.
JOURNAL OF APPLIED MICROBIOLOGY,
2004, 97 (06)
:1166-1177

Rinttilä, T
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Helsinki, Fac Vet Med, Dept Vet Basic Sci, Microbiol Sect, FIN-00014 Helsinki, Finland Univ Helsinki, Fac Vet Med, Dept Vet Basic Sci, Microbiol Sect, FIN-00014 Helsinki, Finland

Kassinen, A
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Helsinki, Fac Vet Med, Dept Vet Basic Sci, Microbiol Sect, FIN-00014 Helsinki, Finland Univ Helsinki, Fac Vet Med, Dept Vet Basic Sci, Microbiol Sect, FIN-00014 Helsinki, Finland

Malinen, E
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Helsinki, Fac Vet Med, Dept Vet Basic Sci, Microbiol Sect, FIN-00014 Helsinki, Finland Univ Helsinki, Fac Vet Med, Dept Vet Basic Sci, Microbiol Sect, FIN-00014 Helsinki, Finland

Krogius, L
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Helsinki, Fac Vet Med, Dept Vet Basic Sci, Microbiol Sect, FIN-00014 Helsinki, Finland Univ Helsinki, Fac Vet Med, Dept Vet Basic Sci, Microbiol Sect, FIN-00014 Helsinki, Finland

Palva, A
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Helsinki, Fac Vet Med, Dept Vet Basic Sci, Microbiol Sect, FIN-00014 Helsinki, Finland Univ Helsinki, Fac Vet Med, Dept Vet Basic Sci, Microbiol Sect, FIN-00014 Helsinki, Finland
[10]
Lactobacilli in the female genital tract in relation to other genital microbes and vaginal pH
[J].
Roennqvist, Per Daniel Johannes
;
Forsgren-Brusk, Ulla Birgitta
;
Hakansson, Eva Elisabeth Grahn
.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA,
2006, 85 (06)
:726-735

Roennqvist, Per Daniel Johannes
论文数: 0 引用数: 0
h-index: 0
机构: Essum AB, SE-90304 Umea, Sweden

Forsgren-Brusk, Ulla Birgitta
论文数: 0 引用数: 0
h-index: 0
机构: Essum AB, SE-90304 Umea, Sweden

Hakansson, Eva Elisabeth Grahn
论文数: 0 引用数: 0
h-index: 0
机构: Essum AB, SE-90304 Umea, Sweden