Quantitative variations in the vaginal bacterial population associated with asymptomatic infections: a real-time polymerase chain reaction study

被引:52
作者
Biagi, E. [1 ]
Vitali, B. [1 ]
Pugliese, C. [1 ]
Candela, M. [1 ]
Donders, G. G. G. [2 ,3 ,4 ]
Brigidi, P. [1 ]
机构
[1] Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy
[2] Femicare Clin Res Women, Tienen, Belgium
[3] Catholic Univ Louvain, Dept Obstet & Gynaecol, Gen Hosp Heilig Hart Tienen, B-3000 Louvain, Belgium
[4] Catholic Univ Louvain, Univ Hosp Gasthuisberg, B-3000 Louvain, Belgium
关键词
GROUP-SPECIFIC PRIMERS; GARDNERELLA-VAGINALIS; PREDOMINANT BACTERIA; LACTOBACILLUS SPP; MYCOPLASMA-HOMINIS; HUMAN FECES; VAGINOSIS; PCR; WOMEN; CANDIDIASIS;
D O I
10.1007/s10096-008-0617-0
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The real-time polymerase chain reaction (PCR) quantification of several vaginal bacterial groups in healthy women and patients developing asymptomatic bacterial vaginosis (BV) and candidiasis (CA) was performed. Statistical analysis revealed that the BV condition is characterised by a great variability among subjects and that it is associated with a significant increase of Prevotella, Atopobium, Veillonella and Gardnerella vaginalis, and a drop in Lactobacillus. On the contrary, the vaginal microflora of healthy women and patients developing CA was found to be homogeneous and stable over time.
引用
收藏
页码:281 / 285
页数:5
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