Age related, structured educational programmes for the management of atopic dermatitis in children and adolescents: multicentre, randomised controlled trial

被引:291
作者
Staab, D
Diepgen, TL
Fartasch, M
Kupfer, J
Lob-Corzilius, T
Ring, J
Scheewe, S
Scheidt, R
Schmid-Ott, G
Schnopp, C
Szczepanski, R
Werfel, T
Wittenmeier, M
Wahn, U
Gieler, U
机构
[1] Univ Hosp Heidelberg, Dept Clin Social Med Occupat & Environm Dermatol, D-69115 Heidelberg, Germany
[2] Humboldt Univ, Charite, Dept Paediat Pulm & Immunol, Berlin, Germany
[3] Univ Erlangen Nurnberg, Dept Dermatol, D-8520 Erlangen, Germany
[4] Univ Giessen, Dept Psychol Med, D-35390 Giessen, Germany
[5] Childrens Hosp, Osnabruck, Germany
[6] Tech Univ Munich, Dept Dermatol & Allergy Biederstein, D-8000 Munich, Germany
[7] Rehabil Clin Children & Adolescents, Sylt, Germany
[8] Hannover Med Sch, Dept Psychosomat, Hannover, Germany
[9] Hannover Med Sch, Dept Dermatol & Allergol, Hannover, Germany
[10] Childrens Hosp Amsterdamer Strasse, Cologne, Germany
[11] Univ Giessen, Dept Psychosomat Med & Psychotherapy, D-35390 Giessen, Germany
来源
BMJ-BRITISH MEDICAL JOURNAL | 2006年 / 332卷 / 7547期
关键词
D O I
10.1136/bmj.332.7547.933
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective To determine the effects of age related, structured educational programmes on the management: of moderate to severe atopic dermatitis ill Childhood and adolescence. Design Multicentre, randomised controlled trial. Setting Seven hospitals in Germany. Participants Parents of children With atopic dermatitis aged 3 months to 7 years (n = 274) and 8-12 years (n = 102), adolescents with atopic dermatitis aged 13-18 years (n = 70), and controls (n = 244, n = 83, and n = 50, respectively). Interventions Group sessions of standardised intervention programmes for atopic dermatitis once weekly for six weeks or no education (control group). Main outcome measures Severity of eczema (scoring of atopic dermatitis scale), subjective severity (standardised questionnaires), and quality of life for parents of affected children aged less than 13 years, over 12 months. Results Significant improvements in severity of eczema and subjective severity were seen in all intervention groups compared with control groups (total score for severity: age 3 months to 7 years - 17.5, 95% confidence intervals - 19.6 to - 15.3 v - 12.2, - 14.3 to - 10.1; age 8-12 years - 16.0, - 20.0 to - 12.0 v - 7.8, - 11.4; - 4.3; and age 13-18 years - 19.7, - 23.7 to - 15.7 v - 5.2, - 10.5 to 0.1). Parents of affected children aged less than 7 years experienced significantly better improvement in all five quality of life subscales, whereas parents of affected children aged 8-12 years experienced significantly better improvement ill three or five quality of life subscales. Conclusion Age related educational programmes for the control of atopic dermatitis ill children and adolescents are effective ill the long term management of the disease.
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页码:933 / 936
页数:6
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