Bacteria seize control by acetylating host proteins

被引:5
作者
Worby, Carolyn A.
Dixon, Jack E.
机构
[1] Univ Calif San Diego, Dept Pharmacol, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA
[3] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA
关键词
D O I
10.1126/science.1128785
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The plague-causing bacterium Yersinia pestis injects toxic proteins into its hosts' cells. One of these interferes with the host's secretion of a protective factor by adding acetyl groups to a signaling kinase, blocking its activation.
引用
收藏
页码:1150 / 1151
页数:2
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