Determination of acetaminophen by thermometric titrimetry

被引：143

作者：

Burgot, G ^{[1
]}

Auffret, F ^{[1
]}

Burgot, JL ^{[1
]}

机构：

[1] FAC PHARM,ANALYT CHEM LAB,F-35043 RENNES,FRANCE

来源：

ANALYTICA CHIMICA ACTA | 1997年 / 343卷 / 1-2期

关键词：

acetaminophen; thermometric titration; pharmaceutical analysis;

D O I：

10.1016/S0003-2670(96)00613-7

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A sensitive, accurate and precise thermometric titration is described for the direct determination of greater than or equal to 75mg of acetaminophen in pure form or in pharmaceutical formulations. Titrations are performed with aqueous sodium hydroxide solution. Excipients tested (starch, talc, lactose) had no effect on the accuracy and precision.

引用

页码：125 / 128

页数：4

共 29 条

[1]

AKHTAR MJ, 1994, J PHARM BIOMED ANAL, V3, P379

[2] THE USE OF SOLUTION THERMOCHEMISTRY IN QUALITY-CONTROL METHODS IN PHARMACEUTICAL ANALYSIS [J].