Toxicity testing with Vibrio fischeri: A comparison between the long term (24 h) and the short term (30 min) bioassay

被引：104

作者：

Backhaus, T

Froehner, K

Altenburger, R

Grimme, LH

机构：

[1] UNIV BREMEN, DEPT BIOL CHEM, D-28334 BREMEN, GERMANY

[2] UFZ HELMHOLTZ CTR ENVIRONM RES, D-04318 LEIPZIG, GERMANY

来源：

CHEMOSPHERE | 1997年 / 35卷 / 12期

关键词：

D O I：

10.1016/S0045-6535(97)00340-8

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The acute bioluminescence inhibition assay using the marine bacterium Vibrio fischeri as the test organism is a widely used short term toxicity test, This paper compares the standard 30 minutes test viith a 24 h assay using the same organism and the same test parameter. For that purpose concentration-response relationships were determined for a set of selected substances, reflecting different modes and mechanisms of action. The results indicate a severe blind spot of the acute biotest: The toxicity of certain specifically acting chemicals is drastically underestimated here, while the chronic biotest gives a more reliable estimate of the toxicity of these substances. (C) 1997 Elsevier Science Ltd.

引用

页码：2925 / 2938

页数：14

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