Human fertility does not decline:: evidence from Sweden

被引:50
作者
Akre, O [1 ]
Cnattingius, S [1 ]
Bergström, R [1 ]
Kvist, U [1 ]
Trichopoulos, D [1 ]
Ekbom, A [1 ]
机构
[1] Karolinska Inst, Dept Med Epidemiol, S-17177 Stockholm, Sweden
关键词
fertility; infertility; subfertility; time to pregnancy; epidemiology; trends; risk factors; education; smoking;
D O I
10.1016/S0015-0282(99)00115-6
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To assess changes in human fertility over time. Design: Time-trend analyses and age-period-cohort modeling. Setting: Sweden, 1983-1993. Patient(s): All primiparous women aged greater than or equal to 20 years during the study period. There were 401,653 women who were identified through the nationwide Medical Birth Register. Intervention(s): None. Main Outcome Measure(s): Risk of subfertility, defined as greater than or equal to 1 year of involuntary childlessness. Result(s): Subfertility problems decreased dramatically over successive maternal birth cohorts. Further, the risk of subfertility increased with age and decreased with increasing formal education. Conclusion(s): A decrease in male fertility cannot be ruled out on the basis of these results, but if present, it is minor and totally outweighed by other favorable developments. As the main explanation for our findings, we propose a decrease in the prevalence of secondary subfertility as a result of the eradication of gonorrhea. (Fertil Steril(R) 1999,71.1066-9. (C) 1999 by American Society for Reproductive Medicine.).
引用
收藏
页码:1066 / 1069
页数:4
相关论文
共 21 条
[1]   Increase in testicular cancer incidence in six European countries: A birth cohort phenomenon [J].
Bergstrom, R ;
Adami, HO ;
Mohner, M ;
Zatonski, W ;
Storm, H ;
Ekbom, A ;
Tretli, S ;
Teppo, L ;
Akre, O ;
Hakulinen, T .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1996, 88 (11) :727-733
[2]  
Bolumar F, 1996, AM J EPIDEMIOL, V143, P578
[3]   Life-style factors and female infertility [J].
Buck, GM ;
Sever, LE ;
Batt, RE ;
Mendola, P .
EPIDEMIOLOGY, 1997, 8 (04) :435-441
[4]   EVIDENCE FOR DECREASING QUALITY OF SEMEN DURING PAST 50 YEARS [J].
CARLSEN, E ;
GIWERCMAN, A ;
KEIDING, N ;
SKAKKEBAEK, NE .
BRITISH MEDICAL JOURNAL, 1992, 305 (6854) :609-613
[5]   SEXUALLY-TRANSMITTED DISEASES, PELVIC INFLAMMATORY DISEASE, AND INFERTILITY - AN EPIDEMIOLOGIC UPDATE [J].
CATES, W ;
ROLFS, RT ;
ARAL, SO .
EPIDEMIOLOGIC REVIEWS, 1990, 12 :199-220
[6]   MODELS FOR TEMPORAL VARIATION IN CANCER RATES .1. AGE PERIOD AND AGE COHORT MODELS [J].
CLAYTON, D ;
SCHIFFLERS, E .
STATISTICS IN MEDICINE, 1987, 6 (04) :449-467
[7]   MODELS FOR TEMPORAL VARIATION IN CANCER RATES .2. AGE PERIOD COHORT MODELS [J].
CLAYTON, D ;
SCHIFFLERS, E .
STATISTICS IN MEDICINE, 1987, 6 (04) :469-481
[8]   A QUALITY STUDY OF A MEDICAL BIRTH REGISTRY [J].
CNATTINGIUS, S ;
ERICSON, A ;
GUNNARSKOG, J ;
KALLEN, B .
SCANDINAVIAN JOURNAL OF SOCIAL MEDICINE, 1990, 18 (02) :143-148
[9]   BODY-MASS INDEX AND OVULATORY INFERTILITY [J].
GRODSTEIN, F ;
GOLDMAN, MB ;
CRAMER, DW .
EPIDEMIOLOGY, 1994, 5 (02) :247-250
[10]   MALE AND FEMALE FACTORS IN FERTILITY [J].
JOFFE, M ;
LI, ZM .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1994, 140 (10) :921-929