Dehydration of threonine esters during tosylation

被引：8

作者：

Somlai, C

Lovas, S

Forgó, P

Murphy, RF

Penke, B

机构：

[1] Univ Szeged, Dept Med Chem, H-6720 Szeged, Hungary

[2] Creighton Univ, Sch Med, Dept Biomed Sci, Omaha, NE 68178 USA

[3] Univ Szeged, Dept Organ Chem, H-6720 Szeged, Hungary

来源：

SYNTHETIC COMMUNICATIONS | 2001年 / 31卷 / 23期

关键词：

D O I：

10.1081/SCC-100107012

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tosylation of N-alpha -protected threonine methyl-and benzyl esters was investigated. Depending on the protecting groups, the composition of the reaction mixtures showed different ratio between O-tosyl-and dehydrothreonine derivatives. The latter was formed exclusively in case of N-alpha -Fmoc-threonine benzyl ester.

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页码：3633 / 3640

页数：8

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