Leishmania-HIV interaction:: Immunopathogenic mechanisms

被引：85

作者：

Wolday, D

Berhe, N

Akuffo, H

Britton, S

机构：

[1] Armauer Hansen Res Inst, Addis Ababa, Ethiopia

[2] Univ Addis Ababa, Inst Pathobiol, Addis Ababa, Ethiopia

[3] Karolinska Inst, Ctr Microbiol & Tumor Biol, Stockholm, Sweden

来源：

PARASITOLOGY TODAY | 1999年 / 15卷 / 05期

关键词：

D O I：

10.1016/S0169-4758(99)01431-3

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Both Leishmania and the human immunodeficiency virus (HIV) can infect and multiply in macrophages, and both can dysregulate the immune system. Recent studies indicate that Leishmania can induce the activation of HIV in latently infected monocytic and T cells. Moreover, HIV can enhance intracellular growth of Leishmania in macrophages. Here, Dawit Wolday and colleagues examine the mechanisms that might be involved in the immunopathogenesis of Leishmania-HIV co-infection.

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页码：182 / 187

页数：6

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