Long-term safety of abatacept in patients with rheumatoid arthritis

被引：30

作者：

Atzeni, Fabiola ^{[1
]}

Sarzi-Puttini, Piercarlo ^{[1
]}

Mutti, Alessandra ^{[1
]}

Bugatti, Serena ^{[2
]}

Cavagna, Lorenzo ^{[2
]}

Caporali, Roberto ^{[2
]}

机构：

[1] Univ Hosp L Sacco, Rheumatol Unit, I-20157 Milan, Italy

[2] Univ Pavia, IRCCS Policlin S Matteo Fdn, Div Rheumatol, Pavia, Italy

来源：

AUTOIMMUNITY REVIEWS | 2013年 / 12卷 / 12期

关键词：

Abatacept; Rheumatoid arthritis; Safety; COSTIMULATION MODULATOR ABATACEPT; INADEQUATE RESPONSE; DOUBLE-BLIND; EFFICACY; METHOTREXATE; INFLIXIMAB; PLACEBO; THERAPY;

D O I：

10.1016/j.autrev.2013.06.011

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Abatacept is a selective T cell co-stimulation modulator that was first approved by the Italian Medicines Agency and reimbursed by the Italian National Health Service when used to treat active rheumatoid arthritis "not sufficiently responsive to other disease-modifying anti-rheumatic drugs (DMARDs) including at least one TNF inhibitor", and is now also approved as a first line biological agent. The aim of this review is to summarise the safety data collected in clinical trials and observational studies. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：1115 / 1117

页数：3

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