Bacteriophage λ:: The untold story

被引：20

作者：

Gottesman, M ^{[1
]}

机构：

[1] Columbia Univ Coll Phys & Surg, Inst Canc Res, New York, NY 10032 USA

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1999年 / 293卷 / 02期

关键词：

bacteriophage lambda; scientific logic; gene regulation; recombination; protein folding;

D O I：

10.1006/jmbi.1999.3137

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The study of bacteriophage lambda has provided key insights into fundamental biological processes. This review recalls some highlights in the history of lambda research, and relates how simple (but elegant) experiments yielded major scientific breakthroughs. What we know about recombination, gene regulation, and protein folding, for example, derives in large part from bacteriophage lambda genetics. Lambda not only represents a model system of scientific logic in a technology-driven age, but continues to reveal new principles of molecular biology. (C) 1999 Academic Press.

引用

页码：177 / 180

页数：4

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