From phagocyte diversity and activation to probiotics: Back to Metchnikoff

被引:60
作者
Mantovani, Alberto [1 ,2 ]
机构
[1] IRCCS Ist Clin Humanitas, Milan, Italy
[2] Univ Milan, Inst Gen Pathol, Milan, Italy
关键词
Macrophage activation; Macrophages; M1/M2; polarization; Probiotics;
D O I
10.1002/eji.200838918
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
in this issue of the European journal of Immunology, Siamon Gordon gives a detailed account of Metchnikoff's life and his achievements (Eur. J. Immunol. 2008. 38: 3257-3264). Looking back at the roots of innate immunity stimulates reflections on open issues in the field. Here, I give a personal view of some of these issues, including myeloid-derived suppressor cells, macrophage polarization and adaptive responses of mononuclear phagocytes.
引用
收藏
页码:3269 / 3273
页数:5
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