Single and Dual Pathologies of the Temporal Lobe: Effects on Cognitive Function in Children with Epilepsy

被引:16
作者
Bigel, Marla G. [2 ]
Smith, Mary Lou [1 ,2 ]
机构
[1] Univ Toronto, Dept Psychol, Mississauga, ON L5L 1C6, Canada
[2] Hosp Sick Children, Dept Psychol, Toronto, ON M5G 1X8, Canada
关键词
temporal lobe epilepsy; children; neuropathology; neuropsychology; hippocampal sclerosis; tumor; cortical dysplasia; cognition;
D O I
10.1006/ebeh.2000.0146
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
The neuropathologies associated with temporal lobe epilepsy (TLE) are heterogeneous. The performance of 61 children with single pathology of hippocampal sclerosis (HS), temporal lobe tumor, or cortical dysplasia (CD) or dual pathology of HS + tumor or HS + CD was examined on measures of intelligence, language, memory, and executive function. Children with single pathologies performed significantly better than did children with HS + CD on all standardized measures of IQ. Children with tumors performed significantly better than children with dual pathology on receptive vocabulary. These results support prior research of an association between neuropathology and cognitive function in children with epilepsy and extend the findings to include additional neuropathologies and measures of cognitive functioning. (C) 2001 Academic Press
引用
收藏
页码:37 / 45
页数:9
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