Cryptosporidium dose response studies:: Variation between isolates

被引:67
作者
Teunis, PFM
Chappell, CL
Okhuysen, PC
机构
[1] Natl Inst Publ Hlth & Environm, RIVM, NL-3720 BA Bilthoven, Netherlands
[2] Univ Texas, Sch Publ Hlth, Ctr Infect Dis, Houston, TX 77030 USA
[3] Univ Texas, Sch Med, Div Infect Dis, Houston, TX 77030 USA
关键词
D O I
10.1111/0272-4332.00014
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The infectivity of three different isolates of the waterborne protozoan parasite Cryptosporidium parvum has been tested in human feeding studies. These three isolates (Iowa, TAMU, and UCP) have different ID(50)s, indicating substantial variation in their infectivity for humans. This finding is of great importance for quantitative risk assessment as it provides strong evidence for heterogeneity in infectivity among isolates of the same species.
引用
收藏
页码:175 / 183
页数:9
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