Chemically diverse modified electrodes: A new approach to the design and implementation of sensor arrays

被引:13
作者
Hsueh, CC [1 ]
Liu, Y [1 ]
Henry, M [1 ]
Freund, MS [1 ]
机构
[1] Lehigh Univ, Dept Chem, Bethlehem, PA 18015 USA
关键词
sensor arrays; electrode arrays; artificial neural networks; pattern recognition; self-assembled monolayers;
D O I
10.1016/S0003-2670(99)00399-2
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
An array of five gold electrodes modified with different substituted alkanethiols has been developed that is sensitive to the identity of a series of similar redox active analytes. A double-potential-step methodology was used to interrogate the electrodes in order to extract a maximum amount of information on a short time-scale. The resulting response patterns, containing 80 variables, were used in conjunction with principal component analysis and artificial neural networks for pattern recognition. The degree of overlapping sensitivity between 80 variables as well as reproducibility from measurement to measurement and array to array is discussed. Finally, a method for normalizing the response patterns in order to produce concentration independent patterns is described. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:135 / 144
页数:10
相关论文
共 35 条
  • [1] Andrieux C. P., 1986, INVESTIGATION RATE 2, P305
  • [2] BARD AJ, 1980, ELECTROCHEMICAL METH
  • [3] PROCESSING OF SIGNALS FROM AN ION-SELECTIVE ELECTRODE ARRAY BY A NEURAL NETWORK
    BOS, M
    BOS, A
    VANDERLINDEN, WE
    [J]. ANALYTICA CHIMICA ACTA, 1990, 233 (01) : 31 - 39
  • [4] COMBINED IMAGING AND CHEMICAL SENSING USING A SINGLE OPTICAL IMAGING FIBER
    BRONK, KS
    MICHAEL, KL
    PANTANO, P
    WALT, DR
    [J]. ANALYTICAL CHEMISTRY, 1995, 67 (17) : 2750 - 2757
  • [5] SELECTIVITY AND SENSITIVITY OF SELF-ASSEMBLED THIOCTIC ACID ELECTRODES
    CHENG, Q
    BRAJTERTOTH, A
    [J]. ANALYTICAL CHEMISTRY, 1992, 64 (17) : 1998 - 2000
  • [6] New organic materials suitable for use in chemical sensor arrays
    Crooks, RM
    Ricco, AJ
    [J]. ACCOUNTS OF CHEMICAL RESEARCH, 1998, 31 (05) : 219 - 227
  • [7] A chemical-detecting system based on a cross-reactive optical sensor array
    Dickinson, TA
    White, J
    Kauer, JS
    Walt, DR
    [J]. NATURE, 1996, 382 (6593) : 697 - 700
  • [8] Multicomponent analysis of heavy metal cations and inorganic anions in liquids by a non-selective chalcogenide glass sensor array
    DiNatale, C
    Davide, F
    Brunink, JAJ
    DAmico, A
    Vlasov, YG
    Legin, AV
    Rudnitskaya, AM
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 1996, 34 (1-3) : 539 - 542
  • [9] Use of compatible polymer blends to fabricate arrays of carbon black-polymer composite vapor detectors
    Doleman, BJ
    Sanner, RD
    Severin, EJ
    Grubbs, RH
    Lewis, NS
    [J]. ANALYTICAL CHEMISTRY, 1998, 70 (13) : 2560 - 2564
  • [10] Trends in odor intensity for human and electronic noses: Relative roles of odorant vapor pressure vs molecularly specific odorant binding
    Doleman, BJ
    Severin, EJ
    Lewis, NS
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (10) : 5442 - 5447