Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China

被引:61
作者
Gu, Min [1 ,2 ]
Zhao, Guo [1 ]
Zhao, Kunkun [1 ]
Zhong, Lei [1 ]
Huang, Junqing [1 ]
Wan, Hongquan [1 ]
Wang, Xiaoquan [1 ,2 ]
Liu, Wenbo [1 ,2 ]
Liu, Huimou [1 ,2 ]
Peng, Daxin [1 ,2 ]
Liu, Xiufan [1 ,2 ]
机构
[1] Yangzhou Univ, Coll Vet Med, Yangzhou 225009, Jiangsu, Peoples R China
[2] Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Peoples R China
关键词
CONTINUED EVOLUTION; GENOME SEQUENCE; DUCKS; H5N5; NOMENCLATURE; CHICKENS;
D O I
10.3201/eid1912.130340
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009-2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may reduce the efficacy of vaccines designed to control these viruses in poultry.
引用
收藏
页码:2021 / 2024
页数:4
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