Mutational analysis of motor proteins

被引：35

作者：

Sweeney, HL ^{[1
]}

Holzbaur, ELF ^{[1
]}

机构：

[1] UNIV PENN,SCH VET MED,DEPT ANIM BIOL,PHILADELPHIA,PA 19104

来源：

ANNUAL REVIEW OF PHYSIOLOGY | 1996年 / 58卷

关键词：

molecular motor; myosin; kinesin; dynein; mutation;

D O I：

10.1146/annurev.physiol.58.1.751

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Mutations in motor proteins, which can arise by design or randomly, provide powerful insights into the normal function of the protein. This review organizes the available data on mutations of members of the myosin, kinesin, and dynein superfamilies of motor proteins. These data contribute to an understanding of the cellular role of the motor proteins as well as provide insights into the fundamental mechanisms of motor function.

引用

页码：751 / 792

页数：42

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