Cancer cells use exosomes as tools to manipulate immunity and the microenvironment

被引:31
作者
Clayton, Aled [1 ]
机构
[1] Cardiff Univ, Dept Pharmacol Oncol & Radiol, Sch Med, Velindre Canc Ctr, Whitchurch Cardiff, Wales
关键词
RESPONSES;
D O I
10.4161/onci.1.1.17826
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Exosomes are small vesicles secreted in relative abundance by cancer cells, which may prove useful as disease markers. However, exosomes also exhibit potent functions; modulating the behavior of immune- and other cells. Bridging our understanding of their molecular phenotype and functional mechanisms will provide key insight into their importance in cancer.
引用
收藏
页码:78 / 80
页数:3
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