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Cancer cells use exosomes as tools to manipulate immunity and the microenvironment
被引:31
作者:

Clayton, Aled
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机构:
Cardiff Univ, Dept Pharmacol Oncol & Radiol, Sch Med, Velindre Canc Ctr, Whitchurch Cardiff, Wales Cardiff Univ, Dept Pharmacol Oncol & Radiol, Sch Med, Velindre Canc Ctr, Whitchurch Cardiff, Wales
机构:
[1] Cardiff Univ, Dept Pharmacol Oncol & Radiol, Sch Med, Velindre Canc Ctr, Whitchurch Cardiff, Wales
关键词:
RESPONSES;
D O I:
10.4161/onci.1.1.17826
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Exosomes are small vesicles secreted in relative abundance by cancer cells, which may prove useful as disease markers. However, exosomes also exhibit potent functions; modulating the behavior of immune- and other cells. Bridging our understanding of their molecular phenotype and functional mechanisms will provide key insight into their importance in cancer.
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页码:78 / 80
页数:3
相关论文
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Cardiff Univ, Sch Med, Velindre Canc Ctr, Dept Pharmacol Radiol & Oncol, Cardiff CF14 2TL, S Glam, Wales Cardiff Univ, Sch Med, Velindre Canc Ctr, Dept Pharmacol Radiol & Oncol, Cardiff CF14 2TL, S Glam, Wales

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Staffurth, John
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Cardiff Univ, Velindre Canc Ctr, Sch Med, Dept Pharmacol Oncol & Radiol,Sect Oncol & Pallia, Cardiff CF14 2TL, S Glam, Wales Cardiff Univ, Velindre Canc Ctr, Sch Med, Dept Pharmacol Oncol & Radiol,Sect Oncol & Pallia, Cardiff CF14 2TL, S Glam, Wales

Mason, Malcolm D.
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Cardiff Univ, Velindre Canc Ctr, Sch Med, Dept Pharmacol Oncol & Radiol,Sect Oncol & Pallia, Cardiff CF14 2TL, S Glam, Wales Cardiff Univ, Velindre Canc Ctr, Sch Med, Dept Pharmacol Oncol & Radiol,Sect Oncol & Pallia, Cardiff CF14 2TL, S Glam, Wales

Clayton, Aled
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h-index: 0
机构:
Cardiff Univ, Velindre Canc Ctr, Sch Med, Dept Pharmacol Oncol & Radiol,Sect Oncol & Pallia, Cardiff CF14 2TL, S Glam, Wales Cardiff Univ, Velindre Canc Ctr, Sch Med, Dept Pharmacol Oncol & Radiol,Sect Oncol & Pallia, Cardiff CF14 2TL, S Glam, Wales