Ratio of branched chain amino acid to tyrosine after hepatectomy

被引：7

作者：

Niguma, T ^{[1
]}

Yumura, M ^{[1
]}

Yamasita, Y ^{[1
]}

Maeda, K ^{[1
]}

Kimura, T ^{[1
]}

Yamamura, M ^{[1
]}

Kodani, J ^{[1
]}

机构：

[1] Tottori Municipal Hosp, Dept Surg, Tottori 6800873, Japan

来源：

SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY | 1999年 / 29卷 / 08期

关键词：

branched chain amino acids; liver resection; Fischer ratio;

D O I：

10.1007/BF02482339

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The roles of branched chain amino acids (BCAAs) and the tyrosine (Tyr) profile after liver resection were investigated using an inexpensive enzymatic method that was recently developed to quantify their concentrations. The preoperative BCAAs-to-Tyr ratio (BTR) was significantly correlated with the preoperative indocyanin green clearance ratio. The BTR decreased immediately after surgery in all patients, but it was significantly lower in those who had undergone major hepatectomies. After the infusion of BCAA-enriched amino acid solution, the BTR increased substantially, being significantly higher in patients who had not suffered an elevation in total bilirubin after liver resection. These findings indicate that this new enzymatic method to quantify the concentration of BCAAs and Tyr is useful to control the infusion of amino acids and to study the role of amino acid metabolization during the perioperative period.

引用

页码：825 / 827

页数：3