Antiviral flavonoid-type C-glycosides from the flowers of Trollius chinensis

被引：56

作者：

Cai, SQ ^{[1
]}

Wang, RF

Yang, XW

Shang, MY

Ma, CM

Shoyama, Y

机构：

[1] Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

[2] Kyushu Univ, Grad Sch Pharmaceut Sci, Fukuoka 812, Japan

来源：

CHEMISTRY & BIODIVERSITY | 2006年 / 3卷 / 03期

关键词：

D O I：

10.1002/cbdv.200690037

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new flavonoid-type C-glycosides, trollisin I (=(IS)-1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5hydroxy-7-nietlioxy-4-oxo4H-[1]benzopyran-8-yl]-2-O-(2-methylbutanoyl)-D-glucitol; 1) and its 2-O-benzoyl congener trollisin II (2), were isolated from Trollius chinensis BUNGE, together with the two known compounds 2 ''-O-(2 '''-methylbutanoyl)isoswertisin (3) and vitexin galactoside (4). All compounds were identified by HR-ESI-MS and in-depth NMR-spectroscopic analyses. In antiviral assays, compound 3 was found to be moderately active towards influenza virus A.

引用

页码：343 / 348

页数：6

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