Acanthamoeba keratitis with live isolates treated with cryosurgery and fluconazole

被引：20

作者：

Amoils, SP ^{[1
]}

Heney, C ^{[1
]}

机构：

[1] Morningside Clin, Dept Ophthalmol, Johannesburg, South Africa

来源：

AMERICAN JOURNAL OF OPHTHALMOLOGY | 1999年 / 127卷 / 06期

关键词：

D O I：

10.1016/S0002-9394(98)00426-7

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

PURPOSE: To report live, active trophozoites in an eye with Acanthamoeba keratitis that resembled Acanthamoeba polyphagia in the anterior chamber fluid obtained by transcorneal tap. METHOD: After prediagnostic therapy had failed, we performed cryosurgery to break the corneal cell walls and treated the patient. with oral fluconazole. RESULTS: The condition resolved after 8 weeks of oral fluconazole therapy. Residual leukoma was treated by corneal graft. CONCLUSION: Live, motile Acanthamoeba can be isolated from an anterior chamber tap; combination therapy with oral fluconazole after corneal cryosurgery may be effective. (Am J Ophthalmol 1999;127:718-720, (C) 1999 by Elsevier Science Inc. All rights reserved.).

引用

页码：718 / 720

页数：3