Plastic changes in the auditory cortex of congenitally deaf cats following cochlear implantation

被引:25
作者
Klinke, R [1 ]
Hartmann, R [1 ]
Heid, S [1 ]
Tillein, J [1 ]
Kral, A [1 ]
机构
[1] Goethe Univ Frankfurt, Inst Physiol 2, D-60590 Frankfurt, Germany
关键词
D O I
10.1159/000046833
中图分类号
R36 [病理学]; R76 [耳鼻咽喉科学];
学科分类号
100104 ; 100213 ;
摘要
Congenitally deaf cats were used as a model for human inborn deafness and auditory deprivation. The deaf cats were supplied with a cochlear implant, chronically exposed to an acoustic environment and conditioned to acoustic stimuli. In case of early implantation the cats learned to make use of the newly gained auditory channel behaviourally. Neurophysiological and fMRI data showed that the central auditory system was recruited, if implantation took place within a sensitive period of <6 months. Copyright (C) 2001 S. Karger AG, Basel.
引用
收藏
页码:203 / 206
页数:4
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