Controlled clinical study of standardized Andrographis paniculata extract in common cold - A pilot trial

被引:56
作者
Melchior, J
Palm, S
Wikman, G
机构
[1] SWEDISH HERBAL INST,VALLBERGA PROD & RES CTR,VALLBERGA,SWEDEN
[2] SWEDISH HERBAL INST,GOTHENBURG,SWEDEN
关键词
Andrographis paniculata; common cold; sinusitis; controlled double blind study;
D O I
10.1016/S0944-7113(97)80002-5
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Kanjang(R) tablets (standardized Andrographis paniculata extract) have proven effective in the initial treatment of commend cold and sinusitis. Kanjang(R) tablets is a herbal formula, which has been developed by the Swedish Herbal Institute in Gothenburg. The tablets have shown a beneficial effect with regards to the subjective experience of initial symptoms of common cold and uncomplicated sinusitis, as well as to the duration of the symptoms. The preparation has been used in the Nordic countries for more than 12 years, mainly for reducing symptoms of common cold and sinusitis, and shortening the duration of the symptoms. In this controlled, double-blind study performed as a pilot trial at the Health Center, Hallehalsan, during the autumn of 1992, conducted in 50 patients, both subjective symptoms as well as duration of the symptoms were significantly reduced. From the results evaluated it is quite clear that Kanjang(R) tablets decrease the subjective symptoms of common cold as well as shortening of the period of sick leave significantly.
引用
收藏
页码:315 / 318
页数:4
相关论文
共 13 条
[1]  
BRAUNWALD, HARRISONS PRINCIPL 1, P677
[2]   STRUCTURE AND STEREOCHEMISTRY OF NEOANDROGRAPHOLIDE, A DITERPENE GLUCOSIDE FROM ANDROGRAPHIS-PANICULATA NEES [J].
CHAN, WR ;
TAYLOR, DR ;
WILLIS, CR ;
BODDEN, RL ;
FEHLHABER, HW .
TETRAHEDRON, 1971, 27 (21) :5081-+
[3]  
Deng W., 1982, Chinese Pharmaceut. Bull., V17, P195
[4]  
GAO WW, 1979, J BETHUNE U MED SCI, V72
[5]  
Gorter K, 1911, RECL TRAV CH PAYS-BA, V30, P151
[6]  
HANCKE J, UNPUB EFFECT ANDROGR
[7]   CONSTITUENTS OF ANDROGRAPHIS-PANICULATA NEES [J].
KLEIPOOL, RJC .
NATURE, 1952, 169 (4288) :33-34
[8]  
*PHARM DEP SICH I, 1975, SICHUAN COMMUNICATIO, P21
[9]  
THAMLIKITKUL V, 1991, J MED ASS THAI OCT
[10]  
WANG CF, CURATIVE EFFECT UPPE