The objectives of this study were to investigate the influence of the nature of the deforestation process on an empirical spatial model of deforestation and to test a remote-sensing-based methodology to define the appropriate spatial entities for modelling deforestation, The study area is located in southern Cameroon, The study included the production and integration in a geographic information system (GIS) of a database of natural and cultural landscape variables, An empirical spatial model of deforestation was developed by relating a set of variables measuring landscape attributes to the frequency of occurrence of deforestation, The main conclusion of the study is that the definition of the spatial entities used to calibrate a spatial model of deforestation has a significant impact on the model design but not, in this case, on the predictive power of the model, The interpretation of the spatial pattern of forest/non-forest interfaces as detected by remote sensing proved to be efficient in identifying regions affected by different deforestation processes. (C) 1997 Elsevier Science Ltd.