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B-cell superantigens

被引：72
作者：
Silverman, GJ [1 ]
机构：
[1] UNIV CALIF SAN DIEGO,THEODORE GILDRED CANC CTR,DEPT MED,LA JOLLA,CA 92093
来源：
IMMUNOLOGY TODAY | 1997年 / 18卷 / 08期
关键词：
D O I：
10.1016/S0167-5699(97)01101-8
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Superantigens (SAgs) are characterized by their ability to interact with T- and B-cell antigen (Ag) receptors outside of the classical Ag-binding groove. Here, Gregg Silverman discusses the molecular basis for the binding of B-cell SAgs, and how they may influence the acquisition of immunocompetence or contribute to the development of immune abnormalities associated with certain inflammatory and infectious diseases.
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收藏
页码：379 / 386
页数：8
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