Lack of platelet response to collagen associated with autoantibodies against glycoprotein (CP) Ia/IIa and Ib/IX leading to the discovery of SLE

被引：2

作者：

Dromigny, A

Triadou, P

Lesavre, P

MorelKopp, MC

Kaplan, C

机构：

[1] HOP NECKER ENFANTS MALAD,HEMATOL LAB,F-75743 PARIS 15,FRANCE

[2] HOP NECKER ENFANTS MALAD,DEPT NEPHROL,F-75743 PARIS 15,FRANCE

[3] INST NATL TRANSFUS SANGUINE,SERV IMMUNOL LEUCOPLAQUETTAIRE,F-75015 PARIS,FRANCE

来源：

HEMATOLOGY AND CELL THERAPY | 1996年 / 38卷 / 04期

关键词：

platelet function; autoantibodies; membrane; glycoproteins; SLE;

D O I：

10.1007/s00282-996-0355-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

An increased bleeding time and a prolonged APTT (activated partial thromboplastin time) observed in a 48-year-old woman led to the-discovery of SLE confirmed by immunological tests. Platelet function and analysis of membrane glycoproteins revealed an isolated impaired collagen induced platelet aggregation and allowed the detection of autoantibodies directed against GpIa/IIa and GpIb/IX.

引用

页码：355 / 357

页数：3

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