cine-substitution of 1-methyl-3,6,8-trinitro-2-quinolone

被引：30

作者：

Nishiwaki, N ^{[1
]}

Tanaka, A ^{[1
]}

Uchida, M ^{[1
]}

Tohda, Y ^{[1
]}

Ariga, M ^{[1
]}

机构：

[1] OSAKA KYOIKU UNIV, DEPT CHEM, KASHIWARA, OSAKA 582, JAPAN

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1996年 / 69卷 / 05期

关键词：

D O I：

10.1246/bcsj.69.1377

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

cine-Substitution of 1-methyl-3,6,8-trinitro-2-quinolone by 1,3-dicarbonyl compounds in the presence of NEt(3) occurred efficiently, affording 4-functionalized 6,8-dinitro-2-quinolone derivatives. The addition intermediate was isolated in the reaction with CH2(CO(2)Et)(2) and EtONa. Conversion of the isolated intermediate into the cine-substituted product was performed. These results indicate that the present cine-substitution proceeds by the addition-elimination mechanism.

引用

页码：1377 / 1381

页数：5

共 21 条

[1]

ANILINES E, 1982, B CHEM SOC JPN, V55, P2174

[2] NUCLEOPHILIC REACTION UPON ELECTRON-DEFICIENT PYRIDONE DERIVATIVES .9. RING TRANSFORMATION OF 1,3-DINITROQUINOLIZIN-4-ONE WITH ENOLATE ANIONS [J].