Imaging soft matter with the atomic force microscope: Cubosomes and hexosomes

被引:72
作者
Neto, C
Aloisi, G
Baglioni, P
Larsson, K
机构
[1] Univ Florence, Dept Chem, I-50121 Florence, Italy
[2] Camurus Lipid Res Fdn, S-22370 Lund, Sweden
来源
JOURNAL OF PHYSICAL CHEMISTRY B | 1999年 / 103卷 / 19期
关键词
D O I
10.1021/jp984551b
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The atomic force microscope has been used to obtain images of colloidal dispersions of liquid crystal phases of cubic and hexagonal structures in water. Particle dimensions are consistent with dynamic light scattering and cryo-TEM data. The images we present in this work demonstrate the potential application of atomic force microscopy in revealing the morphology and structure of very soft matter in situ. This implies being able to detect possible structural modifications of the liquid crystalline phase due to in situ addition of enzymes, salts, polymers, etc. This kind of observation is not possible with other conventional high-resolution techniques.
引用
收藏
页码:3896 / 3899
页数:4
相关论文
共 22 条
[1]   STRUCTURE OF THE CUBOSOME - A CLOSED LIPID BILAYER AGGREGATE [J].
ANDERSSON, S ;
JACOB, M ;
LIDIN, S ;
LARSSON, K .
ZEITSCHRIFT FUR KRISTALLOGRAPHIE, 1995, 210 (05) :315-318
[2]   ON THE SHAPE OF CRYSTALS [J].
ANDERSSON, S ;
JACOB, M ;
LIDIN, S .
ZEITSCHRIFT FUR KRISTALLOGRAPHIE, 1995, 210 (01) :3-4
[3]  
Andersson S, 1997, Z KRISTALLOGR, V212, P334
[4]  
CAPPELLA B, 1997, ENG MED BIOL MAR, P58
[5]   IMAGING CRYSTALS, POLYMERS, AND PROCESSES IN WATER WITH THE ATOMIC FORCE MICROSCOPE [J].
DRAKE, B ;
PRATER, CB ;
WEISENHORN, AL ;
GOULD, SAC ;
ALBRECHT, TR ;
QUATE, CF ;
CANNELL, DS ;
HANSMA, HG ;
HANSMA, PK .
SCIENCE, 1989, 243 (4898) :1586-1589
[6]   A CUBIC PROTEIN-MONOOLEIN-WATER PHASE [J].
ERICSSON, B ;
LARSSON, K ;
FONTELL, K .
BIOCHIMICA ET BIOPHYSICA ACTA, 1983, 729 (01) :23-27
[7]   CUBIC PHASES IN SURFACTANT AND SURFACTANT-LIKE LIPID SYSTEMS [J].
FONTELL, K .
COLLOID AND POLYMER SCIENCE, 1990, 268 (03) :264-285
[8]   Cubic lipid-water phase dispersed into submicron particles [J].
Gustafsson, J ;
LjusbergWahren, H ;
Almgren, M ;
Larsson, K .
LANGMUIR, 1996, 12 (20) :4611-4613
[9]   Submicron particles of reversed lipid phases in water stabilized by a nonionic amphiphilic polymer [J].
Gustafsson, J ;
Ljusberg-Wahren, H ;
Almgren, M ;
Larsson, K .
LANGMUIR, 1997, 13 (26) :6964-6971
[10]   Lipid bilayer standing wave conformations in aqueous cubic phases [J].
Jacob, M ;
Larsson, K ;
Andersson, S .
ZEITSCHRIFT FUR KRISTALLOGRAPHIE, 1997, 212 (01) :5-8