Systemic T-cell activation in stable angina pectoris

被引:20
作者
Jonasson, L [1 ]
Linderfalk, C
Olsson, J
Wikby, A
Olsson, AG
机构
[1] Hogland Hosp, Res Ctr Cardiovasc & Metab Dis, Eksjo, Sweden
[2] Ryhov Hosp, Dept Microbiol, Jonkoping, Sweden
[3] Fac Hlth Sci, Dept Med & Care, Linkoping, Sweden
关键词
D O I
10.1016/S0002-9149(01)02348-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Patients with stable angina pectoris had significantly increased numbers of activated CD4+ T cells in peripheral blood compared with healthy men. The T-cell activation was further supported by significantly higher serum levels of the soluble interleukin-2 receptor. The T-cell response was more pronounced in patients who did not receive statins compared with patients on statin therapy.
引用
收藏
页码:754 / +
页数:4
相关论文
共 18 条
  • [1] C-reactive protein and coronary artery disease:: Additional evidence of the implication of an inflammatory process in acute coronary syndromes
    Abdelmouttaleb, I
    Danchin, N
    Ilardo, C
    Aimone-Gastin, I
    Angioï, M
    Lozniewski, A
    Loubinoux, J
    Le Faou, A
    Guéant, JL
    [J]. AMERICAN HEART JOURNAL, 1999, 137 (02) : 346 - 351
  • [2] T-LYMPHOCYTE ACTIVATION IN STABLE ANGINA-PECTORIS AND AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY
    BLUM, A
    SCLAROVSKY, S
    SHOHAT, B
    [J]. CIRCULATION, 1995, 91 (01) : 20 - 22
  • [3] Evidence for antigen-driven T-cell response in unstable angina
    Caligiuri, G
    Paulsson, G
    Nicoletti, A
    Maseri, A
    Hansson, GK
    [J]. CIRCULATION, 2000, 102 (10) : 1114 - 1119
  • [4] Immune system activation follows inflammation in unstable angina: Pathogenetic implications
    Caligiuri, G
    Liuzzo, G
    Biasucci, LM
    Maseri, A
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1998, 32 (05) : 1295 - 1304
  • [5] CUTHBERT JA, 1981, J IMMUNOL, V126, P2093
  • [6] SUPPRESSION OF LYMPHOID-CELL FUNCTION-INVITRO BY INHIBITION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE BY LOVASTATIN
    CUTTS, JL
    BANKHURST, AD
    [J]. INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, 1989, 11 (08): : 863 - 869
  • [7] FERGUSON FG, 1995, J GERONTOL A-BIOL, V50, P378
  • [8] Halme S, 1997, EUR HEART J, V18, P1095
  • [9] HANSSON GK, 1989, AM J PATHOL, V135, P169
  • [10] Increased proinflammatory cytokines in patients with chronic stable angina and their reduction by aspirin
    Ikonomidis, I
    Andreotti, F
    Economou, E
    Stefanadis, C
    Toutouzas, P
    Nihoyannopoulos, P
    [J]. CIRCULATION, 1999, 100 (08) : 793 - 798