Oxytocin Makes a Face in Memory Familiar

被引：291

作者：

Rimmele, Ulrike ^{[1
,2
]}

Hediger, Karin ^{[2
]}

Heinrichs, Markus ^{[2
]}

Klaver, Peter ^{[3
]}

机构：

[1] NYU, Dept Psychol, New York, NY 10003 USA

[2] Univ Zurich, Dept Psychol Clin Psychol & Psychobiol, CH-8050 Zurich, Switzerland

[3] Univ Zurich, Univ Childrens Hosp Zurich, Magnet Resonance Ctr, CH-8032 Zurich, Switzerland

来源：

JOURNAL OF NEUROSCIENCE | 2009年 / 29卷 / 01期

基金：

瑞士国家科学基金会;

关键词：

oxytocin; social; face; recognition; memory; neuropeptide; HUMAN EXTRASTRIATE CORTEX; SOCIAL RECOGNITION; NEUROHYPOPHYSEAL PEPTIDES; NEUROENDOCRINE BASIS; NEURAL CIRCUITRY; AMYGDALA; HUMANS; VASOPRESSIN; BRAIN; ORGANIZATION;

D O I：

10.1523/JNEUROSCI.4260-08.2009

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Social recognition is the basis of all social interactions. Here, we show that, in humans, the evolutionarily highly conserved neuropeptide oxytocin, after intranasal administration, specifically improves recognition memory for faces, but not for nonsocial stimuli. With increased oxytocin levels, previously presented faces were more correctly assessed as "known," whereas the ability of recollecting faces was unchanged. This pattern speaks for an immediate and selective effect of the peptide strengthening neuronal systems of social memory.

引用

页码：38 / 42

页数：5

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