Asymmetric catalytic carbon-carbon bond formations in a fluorous biphasic system based on perfluoroalkyl-BINOLs

被引：49

作者：

Tian, Y ^{[1
]}

Yang, QC ^{[1
]}

Mak, TCW ^{[1
]}

Chan, KS ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Univ Grants Comm Area Excellence Scheme, Inst Mol Technol Drug Discovery & Synth, Open Lab Chirotechnol,Dept Chem, Shatin, Hong Kong, Peoples R China

来源：

TETRAHEDRON | 2002年 / 58卷 / 20期

关键词：

asymmetric fluorous biphasic catalysis; perfluoroalkylbinaphthols;

D O I：

10.1016/S0040-4020(02)00218-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically active 1, 1'-binaphthols (BINOLS) substituted at the 4,4'; 6,6' and 4,4',6,6' positions with perfluoroalkyl groups have been synthesized. Asymmetric diethylzinc and triethyl aluminum addition to aryl aldehydes in a fluorous biphasic system catalyzed by these perfluoroalkyl-BINOL-titanium complexes have been accomplished with good enantiomeric excess obtained. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：3951 / 3961

页数：11

共 38 条

[1]

[Anonymous], 1999, Comprehensive Asymmetric Catalysis

[2]

BARTLETT PD, 1973, ORG SYNTH, V5, P196

[3] Copper-catalyzed aerobic oxidation of alcohols under fluorous biphasic conditions [J].