Nanochannels fabricated in polydimethylsiloxane using sacrificial electrospun polyethylene oxide nanofibers

被引:30
作者
Bellan, Leon M. [1 ]
Strychalski, Elizabeth A. [2 ]
Craighead, Harold G. [1 ]
机构
[1] Cornell Univ, Sch Appl & Engn Phys, Ithaca, NY 14853 USA
[2] Cornell Univ, Dept Phys, Ithaca, NY 14853 USA
来源
JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B | 2008年 / 26卷 / 05期
基金
美国国家科学基金会;
关键词
D O I
10.1116/1.2975199
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
The authors have used electrospun polyethylene oxide nanofibers as sacrificial templates to form nanofluidic channels in polydimethylsiloxane (PDMS). By depositing fibers on silicon templates incorporating larger structures, the authors demonstrate that these nanochannels can be integrated easily with microfluidics. They use fluorescence microscopy to image channels filled with dye solution. The utility of the hybrid micro- and nanofluidic PDMS structures for single molecule observation and manipulation was demonstrated by introducing single molecules of lambda-DNA into the channels. This nanofabrication technique allows the simple construction of integrated micro- and nanofluidic PDMS structures without lithographic nanofabrication techniques. (C) 2008 American Vacuum Society.
引用
收藏
页码:1728 / 1731
页数:4
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