Human retroviral sequences associated with extracellular particles in autoimmune diseases: epiphenomenon or possible role in aetiopathogenesis?

被引:26
作者
Perron, H [1 ]
Seigneurin, JM
机构
[1] BioMerieux SA, F-69280 Marcy Letoile, France
[2] Fac Med, Lab Virol Med Mol, F-38700 La Tronche, France
关键词
retrovirus; superantigen; autoimmunity; multiple sclerosis; diabetes; systemic lupus;
D O I
10.1016/S1286-4579(99)80027-6
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Publications describing retroviral sequences associated with extracellular particles in Sjogren's syndrome or systemic lupus erythematosus, multiple sclerosis, and type I diabetes present novel arguments and raise complex questions about eventual relationships between retroviruses and autoimmunity. They are presented and discussed in the present review, preceded by an overview of the biology of retroviral elements. (C) Elsevier, Paris.
引用
收藏
页码:309 / 322
页数:14
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