B cell recognition of membrane-bound antigen: an exquisite way of sensing ligands

被引：91

作者：

Carrasco, Yolanda R. ^{[1
]}

Batista, Facundo D. ^{[1
]}

机构：

[1] Canc Res UK London Res Inst, London WC2A 3PX, England

来源：

CURRENT OPINION IN IMMUNOLOGY | 2006年 / 18卷 / 03期

关键词：

D O I：

10.1016/j.coi.2006.03.013

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

B cell recognition of membrane-bound antigens leads to the formation of an immunological synapse and efficient B cell activation. Ongoing research has been directed towards identifying the parameters that regulate this process. Furthermore, considerable attention has also been focused on the cell types that mediate presentation of intact antigens to B cells, as well as on the mechanisms that underlie it. Whilst there are still many unanswered questions, recent developments in these areas begin to shed light on an emerging field.

引用

页码：286 / 291

页数：6

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