DNA profiling;
F-ST;
F-IS;
inbreeding coefficient;
forensic identification;
population genetics;
D O I:
10.1016/S0379-0738(99)00087-0
中图分类号:
DF [法律];
D9 [法律];
R [医药、卫生];
学科分类号:
0301 ;
10 ;
摘要:
The importance of allowing for recent shared ancestry when calculating forensic match probabilities has been recognised for some time. Within-subpopulation inbreeding will also affect the match probability, and ignoring these effects can lead to an overstatement of the strength of the DNA evidence against a defendant. However, inbreeding can be readily accounted for in match probabilities by incorporating the inbreeding coefficient F-IS into calculations. We derive the necessary formulae, and demonstrate the effect of including F-IS (in addition to F-ST) in the equations. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
机构:
UNIV LONDON, UNIV LONDON QUEEN MARY & WESTFIELD COLL, SCH BIOL SCI, LONDON E1 4NS, ENGLANDUNIV LONDON, UNIV LONDON QUEEN MARY & WESTFIELD COLL, SCH BIOL SCI, LONDON E1 4NS, ENGLAND
BALDING, DJ
NICHOLS, RA
论文数: 0引用数: 0
h-index: 0
机构:
UNIV LONDON, UNIV LONDON QUEEN MARY & WESTFIELD COLL, SCH BIOL SCI, LONDON E1 4NS, ENGLANDUNIV LONDON, UNIV LONDON QUEEN MARY & WESTFIELD COLL, SCH BIOL SCI, LONDON E1 4NS, ENGLAND
机构:
UNIV LONDON, UNIV LONDON QUEEN MARY & WESTFIELD COLL, SCH BIOL SCI, LONDON E1 4NS, ENGLANDUNIV LONDON, UNIV LONDON QUEEN MARY & WESTFIELD COLL, SCH BIOL SCI, LONDON E1 4NS, ENGLAND
BALDING, DJ
NICHOLS, RA
论文数: 0引用数: 0
h-index: 0
机构:
UNIV LONDON, UNIV LONDON QUEEN MARY & WESTFIELD COLL, SCH BIOL SCI, LONDON E1 4NS, ENGLANDUNIV LONDON, UNIV LONDON QUEEN MARY & WESTFIELD COLL, SCH BIOL SCI, LONDON E1 4NS, ENGLAND