Allowing for within-subpopulation inbreeding in forensic match probabilities

被引:44
作者
Ayres, KL
Overall, ADJ
机构
[1] Univ Reading, Dept Appl Stat, Reading RG6 6FN, Berks, England
[2] Univ London Queen Mary & Westfield Coll, Sch Biol Sci, London E1 4NS, England
基金
英国生物技术与生命科学研究理事会; 英国工程与自然科学研究理事会;
关键词
DNA profiling; F-ST; F-IS; inbreeding coefficient; forensic identification; population genetics;
D O I
10.1016/S0379-0738(99)00087-0
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
The importance of allowing for recent shared ancestry when calculating forensic match probabilities has been recognised for some time. Within-subpopulation inbreeding will also affect the match probability, and ignoring these effects can lead to an overstatement of the strength of the DNA evidence against a defendant. However, inbreeding can be readily accounted for in match probabilities by incorporating the inbreeding coefficient F-IS into calculations. We derive the necessary formulae, and demonstrate the effect of including F-IS (in addition to F-ST) in the equations. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:207 / 216
页数:10
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