Scar Zones: Region-Specific Differences in Skin Tension May Determine Incisional Scar Formation

被引：53

作者：

Wong, Victor W.

Levi, Kemal

Akaishi, Satoshi

Schultz, Geoffrey

Dauskardt, Reinhold H. ^{[1
]}

机构：

[1] Stanford Univ, Dept Mat Sci & Engn, Stanford, CA 94305 USA

来源：

PLASTIC AND RECONSTRUCTIVE SURGERY | 2012年 / 129卷 / 06期

关键词：

MECHANICAL-PROPERTIES; IN-VIVO; TISSUE; MODEL; ELASTICITY; BEHAVIOR; AGE;

D O I：

10.1097/PRS.0b013e31824eca79

中图分类号：

R61 [外科手术学];

学科分类号：

100210 [外科学];

摘要：

Regional differences in skin biomechanical properties may affect how physical cues modulate postinjury fibrosis. We demonstrate that variations in skin biomechanical properties can be precisely characterized using noninvasive technologies and propose the presence of region-specific scar zones that are predisposed to scar formation. Region-, wound-, and patient-specific stress shielding may be necessary to optimally control the mechanical environment and improve scar appearance. Copyright © 2012 by the American Society of Plastic Surgeons.

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收藏

页码：1272 / 1276

页数：5

相关论文

共 28 条

[1]

MECHANICAL-PROPERTIES AND YOUNGS MODULUS OF HUMAN-SKIN INVIVO [J].

AGACHE, PG ;

MONNEUR, C ;

LEVEQUE, JL ;

DERIGAL, J .

ARCHIVES OF DERMATOLOGICAL RESEARCH, 1980, 269 (03) :221-232

[2]

The relationship between keloid growth pattern and stretching tension - Visual analysis using the finite element method [J].

Akaishi, Satoshi ;

Akimoto, Masataka ;

Ogawa, Rei ;

Hyakusoku, Hiko .

ANNALS OF PLASTIC SURGERY, 2008, 60 (04) :445-451

[3]

The Tensile Reduction Effects of Silicone Gel Sheeting [J].

Akaishi, Satoshi ;

Akimoto, Masataka ;

Hyakusoku, Hiko ;

Ogawa, Rei .

PLASTIC AND RECONSTRUCTIVE SURGERY, 2010, 126 (02) :109E-111E

[4]

Alenghat Francis J, 2002, Sci STKE, V2002, ppe6, DOI 10.1126/stke.2002.119.pe6

[5]

Mechanics of scars [J].

Cerda, E .

JOURNAL OF BIOMECHANICS, 2005, 38 (08) :1598-1603

[6]

Is there an ideal animal model to study hypertrophic, scarring? [J].

Christovao Ramos, Maria Luiza ;

Gragnani, Alfredo ;

Ferreira, Lydia M. .

JOURNAL OF BURN CARE & RESEARCH, 2008, 29 (02) :363-368

[7]

Biomechanical behavior of scar tissue and uninjured skin in a porcine model [J].

Corr, David T. ;

Gallant-Behm, Corrie L. ;

Shrive, Nigel G. ;

Hart, David A. .

WOUND REPAIR AND REGENERATION, 2009, 17 (02) :250-259

[8]

ELASTIC PROPERTIES OF HUMAN SKIN - RELATION TO AGE, SEX, AND ANATOMICAL REGION [J].

CUA, AB ;

WILHELM, KP ;

MAIBACH, HI .

ARCHIVES OF DERMATOLOGICAL RESEARCH, 1990, 282 (05) :283-288

[9]

Tissue cells feel and respond to the stiffness of their substrate [J].

Discher, DE ;

Janmey, P ;

Wang, YL .

SCIENCE, 2005, 310 (5751) :1139-1143

[10]

Durkaya S, 2005, TEX HEART I J, V32, P544