End-stage renal disease associated with familial Mediterranean fever

被引：16

作者：

Tomiyama, N ^{[1
]}

Oshiro, S ^{[1
]}

Higashiuesato, Y ^{[1
]}

Yamazato, M ^{[1
]}

Sakima, A ^{[1
]}

Tana, T ^{[1
]}

Tozawa, M ^{[1
]}

Muratani, H ^{[1
]}

Iseki, K ^{[1
]}

Takishita, S ^{[1
]}

机构：

[1] Univ Ryukyus, Dept Internal Med 3, Nishihara, Okinawa 9030215, Japan

来源：

INTERNAL MEDICINE | 2002年 / 41卷 / 03期

关键词：

periodic fever; amyloidosis; kidney; dialysis; MEFV gene; colchicine;

D O I：

10.2169/internalmedicine.41.221

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 39-year-old man had been suffering from periodic fever since childhood. He was started on hemodialysis due to secondary amyloidosis on December 2000. The patient was believed to have Familial Mediterranean fever (FMF) because of recurrent fever with peritonitis, arthritis and inflammatory changes and secondary amyloidosis in his kidneys, heart and colon. No other family member had recurrent fever. IL-6, TNF, and dopamine beta-hydroxylase were not increased in the febril phase. The patient was homozygous for the M6941 mutation. We report the first Japanese case of FMF associated with amyloidosis and confirmed by a gene mutation.

引用

页码：221 / 224

页数：4

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