Solving the WAVE function

被引:26
作者
Blagg, SL [1 ]
Insall, RH [1 ]
机构
[1] Univ Birmingham, Sch Biosci, Birmingham B15 2TT, W Midlands, England
关键词
D O I
10.1038/ncb0404-279
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
SCAR/WAVE proteins are central regulators of cell motility that coordinate actin reorganization through activation of the Arp2/3 complex. Their activity is controlled by a large complex with four other members. A new study contradicts earlier work by suggesting that the entire complex is required for SCAR/WAVE activity at the leading edge.
引用
收藏
页码:279 / 281
页数:3
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